MiR-208 is related to various cardiac processes, including increased cardiac fibrosis via THRAP-1 (Thyroid-Hormone-Receptor-Associated Protein 1) inhibition, right ventricular hypertrophy by inhibiting the Mef2 axis, and negative regulation of the SOX6 (SRY-Box Transcription Factor 6) gene associated with cardiac hypertrophy [100]. The gene discussed is SOX6; the disease is fibrosis.