VEGFA and Infertility: After extracting primordial follicles from young female mice and transplanting fibrin-encapsulated follicles into infertile mice, Kniazeva et al. demonstrated that while all infertile mice resumed cycling, live births were achieved only when the transplanted follicles were encapsulated in fibrin hydrogels loaded with vascular endothelial growth factor (VEGF) [53].