MBP and myeloid sarcoma: In MS, this imbalance results in immune-mediated myelin destruction, axonal damage and progressive neurodegeneration driven mainly by autoreactive CD4+ T cells, particularly Th1 and Th17 subsets, which recognize CNS antigens such as myelin basic protein (MBP) and myelin oligodendrocyte glycoprotein (MOG) among other myelin antigens [4].