The T2D results of this study corroborate previous findings reported in T2D, whereby the increased Ang II and decreased Ang 1-7 concentration were directly proportional to significantly increased HOMA-IR and HbAlc indicative of insulin resistance and overt hyperglycemia, respectively, in the T2D group compared to the NPD group (see Table 1 and Table 2). This evidence concerns the gene ANGPT1 and Insulin resistance.