The Gene Set Enrichment Analysis (GSEA) demonstrated that the gene sets involved in inflammation signaling were enriched in the high-TG2 HCC group: IL6-JAK-STAT3 signaling, IL2-STAT5 signaling, the inflammatory response, and TNFα signaling via NFKB (Figure 5C). Here, NFKB1 is linked to hepatocellular carcinoma.