The results from Phenolyzer demonstrated that the MYC (TF) has the most significant associations with PCa cases, and the hub genes of the upregulated group (RAD54L, E2F7, CCNB1, CCNA2) and the downregulated group of genes (TOP2A, CDC20, UBE2C, BUB1B, CCNB2, AURKA) as shown in Figure S12. Here, UBE2C is linked to posterior cortical atrophy.