GlueGO and GluePedia enrichment analysis results showed that CCNB1, ESPL1, MKI67, NDC8, BUB1B, CDC20, CCNB1, AURKA, CENPE, DLGAP5, UBE2C, and TOP2A genes were associated with cell cycle and apoptosis, activation of the p53 signaling pathway, tumor suppression, and cell cycle arrest [50,51], alongside a mitotic checkpoint serine kinase that has been documented in PCa [52]. This evidence concerns the gene ESPL1 and neoplasm.