The identified YBX1, MYC, and E2F4 TFs were associated mainly with DOIDs (malignant neoplasm of the prostate and prostate carcinoma) and KEGG pathways for disease-enriched cell cycle, pathways in cancer, the FoxO signaling pathway, prostate cancer, the PI3K-Akt signaling pathway, and the p53 signaling pathway, which are considered to be associated with cancer prognosis. This evidence concerns the gene E2F4 and prostate cancer.