CYP27A1 and type 1 diabetes mellitus: Nyman et al. reported that STZ-induced T1DM mice had higher levels of glucose, glycated haemoglobin (HbA1c), and cross-linked C-telopeptide of type I collagen (CTX), as well as reduced levels of propeptide of type 1 procollagen (P1NP), trabecular and cortical parameters, bone stiffness, force, and bending strength after eight weeks of confirmed T1DM [13].