MMP9 and neoplasm: Using murine models—including Mmp9−/− mice and anti-Ly6G antibody-mediated neutrophil depletion—experimental evidence reveals that 14,15-epoxyeicosatrienoic acid (14,15-EET) initiates a pro-metastatic cascade involving neutrophil-dependent MMP9 production, which both enhances angiogenesis and disrupts tumor dormancy [172].