It has been reported that breast milk from women with subclinical mastitis exhibits a predominant Th1/proinflammatory cytokine profile, including TNF-α, IL-6, IL-8, IL-17, RANTES, IL-12p40/70, IFN-α, IFN-γ, CXCL-9, IP-10, MIP-1α, and MIP-1β [18]. This evidence concerns the gene TNF and mastitis.