Neuropathologically, PSP is characterized by abnormal accumulation of tau protein in the form of globose neurofibrillary tangles (NFTs), tufted astrocytes (TA), oligodendroglial coiled bodies (CB) and neuropil threads (NT) in the basal ganglia, brainstem, cortical regions, and cerebellum [4]. This evidence concerns the gene MAPT and supranuclear palsy, progressive, 1.