In the current study, it was revealed that in pathological aging associated with cardiovascular diseases, activation of the innate immunity component CD14+ monocytes (p = 0.014), a decrease in the adaptive link between the immune system and cytotoxic T-lymphocytes CD8+ (p = 0.046), and a decrease in the intracellular production of GM-CSF by lymphocytes (p = 0.013) are of great importance. The gene discussed is CSF2; the disease is cardiovascular disorder.