In 2020, Kim et al. reported that fecal microbiota transplantation (FMT) from wild-type donor mice into ADLPAPT transgenic mice (a model of AD-like pathology with amyloid plaques and neurofibrillary tangles) effectively alleviated AD-related pathological features, including Aβ plaque deposition, tau pathology, and cognitive impairment [17]. The gene discussed is MAPT; the disease is Alzheimer disease.