To investigate the concrete molecular mechanism of RPLP2 in regulating ferroptosis, we conducted a correlation analysis of RPLP2 and key ferroptosis regulators in TCGA DLBCL samples to show that RPLP2 is significantly positively associated with the ferroptosis suppressor genes FXN and GPX4 (Figure 4A,B and Figure S2A) and negatively linked to ferroptosis-driver genes BECN1 and ALOX12 (Figure 4C,D and Figure S2B). This evidence concerns the gene FXN and diffuse large B-cell lymphoma.