LCN2 and chronic kidney disease: Although several biomarkers of CKD have been identified, including urinary N-acetyl-D-aminoglycosides (NAG), neutrophil gelatinase-associated lipid transport protein (NGAL), and kidney injury molecule-1 (KIM-1) [12,13], it is still necessary to find effective targets for alleviating or treating the progression of CKD.