Shamseldin et al. identified two homozygous THSD1 mutations (C206Y and R224X) in two Saudi families with NIHF [13], while Abdelrahman et al. reported a novel homozygous eight-nucleotide deletion (c.1163-1170delGGCCAGCC) in four Emirati siblings with NIHF, accompanied by congenital cardiac defects and hemangiomas [14]. This evidence concerns the gene THSD1 and Non-immune hydrops fetalis.