PAX8 and Insulin resistance: These genes are involved in various signaling pathways, including those related to insulin resistance and secretion (such as ATM, PTPRN2, PSMD10, and NSF), adipogenesis (notably SLC25A24 and PAX8), inflammatory processes (including TNFRSF8 and SLIT3), and mitochondrial functions (like PM20D1 and LCLAT1).