Aims: We aimed to investigate the gene expression of transforming growth factors (TGFB1, TGFB2, TGFB3) in peripheral blood mononuclear cells (PBMCs) isolated from the blood of patients with unruptured intracranial aneurysms (UIAs) and ruptured intracranial aneurysms (RIAs), and from a control group. This evidence concerns the gene TGFB2 and Dilatation of the cerebral artery.