HES1 and central nervous system cancer: miR-9 targets the forkhead box protein G1 (FoxG1), hairy and enhancer of split-1 (Hes1) or homolog of the Drosophila tailless gene (TLX), CREB, and neurofibromin (NF1) genes for neuronal development [141], whereas the aberrant expression of miR-9 is linked with the glioma via targeting v-Myc avian myelocytomatosis viral oncogene homolog (Myc) and POU class 5 homeobox 1 (OCT4) in human glioma [142].