For example, miR-128 plays a crucial role in nervous system development by targeting Forkhead Box M1, cAMP response element-binding protein (CREB), splicing factor SC35, and LIM domain kinase 1 (Limk1) [138], and has also been linked to various types of brain cancer via targeting STAT5B and KRAS genes [139,140]. Here, CREB1 is linked to brain cancer.