Osthole can inhibit the PI3K/Akt signaling pathway in various cancer cells, such as in endometrial carcinoma, bladder cancer, retinoblastoma, cervical cancer, head and neck squamous cell carcinoma, and gastric cancer, which causes cancer cell proliferation, migration, invasion, and death [25,26,27,29,30,36]. This evidence concerns the gene AKT1 and cervical cancer.