An extensive IHC workup was performed and was unrevealing with negative staining for carcinoma (CAM5.2, pancytokeratin, CK7, CK20), melanoma (S100, SOX10, HMB-45, Melan-A), hematolymphoid markers (CD45, CD43, CD3, CD20, CD30, CD4), myeloid markers (CD34, CD117), myoid markers (SMA, desmin), neuroendocrine markers (CD56, synaptophysin, chromogranin, NSE), pDC markers (CD123, CD303), histiocytic markers (CD68, CD163, CD1a, langerin), and follicular dendritic cell marker (CD21). Here, CD163 is linked to melanoma.