The pertinent negative markers include histiocytic markers (CD163, CD14, CD1a, langerin), FDC markers (CD21, CD23, CD35, clusterin, CXCL13), hematolymphoid markers (CD45, CD3, CD20, CD79a), vascular markers (CD31, CD34), melanoma markers (melanA, SOX10, HMB45, S100), and others (ALK, CD30). This evidence concerns the gene PECAM1 and melanoma.