Cox proportional hazards analysis indicated that a history of receiving COVID-19 vaccinations (three or more times) at the initial visit, PS, jaundice, high TNM factors, no surgery, no chemotherapy, and high tumor markers including carcinoembryonic antigen (CEA) and carbohydrate antigen (CA) 19-9 significantly affected the overall survival (OS) (Table 2). Here, CEACAM5 is linked to COVID-19.