PARP1 and ovarian carcinoma: Poly ADP-ribose polymerase (PARP) inhibitors (PARPi) are a well-established maintenance therapy in stage III and IV ovarian cancer, with evidence of efficacy, especially in patients with germline and/or somatic pathogenic variants (PVs) in the BRCA1/2 genes and in patients with homologous recombination deficiency.