In the group with a PSA of 0.21 ≤ 0.5 ng/mL, with local tumor detection and lymph node metastases, a locally limited therapy option in the sense of initiating radiation therapy was used in 5/8 (62.5%) patients, overall, a locally limited therapy option in 7/8 (87.5%) patients, and systemic therapy in only 1/8 (12.5%). This evidence concerns the gene KLK3 and neoplasm.