DCIS-associated MECs exhibit altered gene expression profiles, including reduced levels of tumor-suppressive markers such as laminin-1, smooth muscle myosin heavy chain (SMMHC), CD10, cytokeratin 14 (CK14), p63, or calponin, along with increased expression of oncogenic factors like chemokine (C-X-C motif) ligand 14 (CXCL14) and αvβ6 integrin. Here, KRT14 is linked to ductal breast carcinoma in situ.