Among the above gene pathways, glutathione S-transferase D7 and xanthine dehydrogenase were differentially regulated in the drug metabolism-other enzymes pathway, while filamin-A-like isoform X1 and rho guanine nucleotide exchange factor 11 isoform X1 genes were differentially regulated in the proteoglycans in cancer pathway (Figure 2B). The gene discussed is XDH; the disease is cancer.