REN and cancer: For the MF treatment group, a total of 14 gene pathways were found to be enriched, including drug metabolism-other enzymes, proteoglycans in cancer, circadian rhythm—fly, caffeine metabolism, the renin–angiotensin system, drug metabolism—cytochrome P450, chemical carcinogenesis—DNA adducts, metabolism of xenobiotics by cytochrome P450, platinum drug resistance, renin secretion, pathways in cancer, glutathione metabolism, longevity regulating pathway—worm, and axon regeneration.