AARS1 and gastric cancer: In gastric cancer cells, alanyl-tRNA synthetase 1 (AARS1) translocates into the nucleus, directly catalyzing the Kla of Yes-associated protein (YAP) at position K90 and TEA domain transcription factor 1 (TEAD1) at position K108, thereby activating the expression of downstream target genes and promoting the proliferation of tumor cells [67].