SOD1 and cancer: A study conducted by Jayakumar et al. shows that carvacrol protects the liver from diethylnitrosamine (DEN)-induced hepatocellular carcinogenesis by reducing lipid peroxidation, restoring key liver enzymes (AST, ALT, ALP, LDH, cGT), and enhancing antioxidant defenses (SOD, CAT, GPx, GR, GSH) while selectively inducing apoptosis in cancer cells without harming normal liver tissue [70].