In addition, Kordasti et al. reported that the serum level of IL-10 in high-risk MDS patients is higher compared to those with low-risk MDS [33]; a meta-analysis also identified that genotype correlated with high expression of IL-10 (−592 CC) is correlated with a lower level of hemoglobin and poorer prognosis [34]. This evidence concerns the gene IL10 and myelodysplastic syndrome.