It is an active compound extracted from blueberries and grapes.(1)PTE treatment independently inhibited cell proliferation and viability while inducing apoptosis by targeting COX2 in lung cancer [174].(2)PTE inhibited breast cancer metastasis by the NF-kB pathway [175].(3)PTE inhibited irradiation-resistant glioma stem cells by modulating the GPR78/miR-205 axis.(4)PTE enhanced the sensitivity of cisplatin-resistant human bladder cancer cells harboring oncogenic HRAS [176]. Here, GPR78 is linked to glioma.