Likewise, interferon response genes (including TLR3, MX1, RSAD2, IFI44, IFI27, IFIT1, and IFIT3), and chemokine genes (including CCL7, CXCL10, CXCR1, and CCL25) were significantly increased in PM-treated MM tumor tissues, whereas panobinostat showed minimal effects at equivalent doses (Fig. 2c). This evidence concerns the gene TLR3 and neoplasm.