SMARCB1 and meningioma: Notably, NF2-cluster 1 included samples with inactivating SMARCB1 mutations (Fig. 5d), which are associated with multiple meningiomas and atypical histopathological subtypes.67, 68, 69 However, clinical follow-up data for these patients is unavailable to confirm increased aggressiveness in NF2-cluster 1.