Diagnosis is based on the Updated Diagnostic Criteria for NF2 and Schwannomatosis (2022) (Supplementary Material Table S2[online oly]).16Management typically involves surgical resection of vestibular schwannomas.13For tumors smaller than 3 cm, hearing preservation is achievable in 65% of patients, although surgical risks increase with tumor size.13Brigatinib, a derivative of anaplastic lymphoma kinase inhibitor-1 (ALK-IN-1), has emerged as a potential treatment for NF2-associated tumors.17 This evidence concerns the gene NF2 and schwannomatosis.