As listed in Table 3 and shown in Fig. 7A, PLAUR was significantly positively correlated with CD8+ T-cell biomarkers (CD8A), CD4+ T-cell biomarkers, M1 macrophage biomarkers (NOS2, IRF5 and PTGS2), M2 macrophage biomarkers (CD163, VSIG4 and MS4A4A), neutrophil biomarkers (CEACAM8, ITGAM and CCR7) and dendritic cell biomarkers (HLA-DPB1, HLA-DPQ1, HLADRA, HLA-DPA1, CD1C, NRP1 and ITGAX) in NSCLC. The gene discussed is IRF5; the disease is non-small cell lung carcinoma.