PRL and amyotrophic lateral sclerosis: In the sensitivity analysis, after excluding individuals with a follow-up of less than 4 years, a thinner PRL (per SD increase HR [95% CI] = 0.84 [0.72, 0.99]; p = 0.040) and a thicker RPE (per SD increase HR [95% CI] = 1.16 [1.01, 1.33]; p = 0.041) was still associated with higher ALS risk, while INL was not (per SD increase HR [95% CI] = 1.05 [0.79, 1.38]; p = 0.741).