This study also elaborated that most of the compounds that showed high dual inhibition of AChE and BACE1 were triterpene saponins belonging to the plant Centella asiatica (L.)Urb., highlighting their affinity for the active sites of both proteins as well as emphasizing the high potency of C. asiatica to be used for the treatment of Alzheimer’s disease. This evidence concerns the gene ACHE and early-onset autosomal dominant Alzheimer disease.