Then, it could be because they have a higher level of insulin resistance despite controlling for factors such as body mass index or family history [57,58] and also because according to a survey carried out among doctors from European centers, they reported feeling more comfortable using traditional methods such as the oral glucose tolerance test and, at a biochemical level, they prefer to analyze insulin values, therefore that it is unlikely that there will be marked interest to study other biomarkers [59]. The gene discussed is INS; the disease is Insulin resistance.