Perhaps the most prominent example of overlapping genes was the subset of differentially regulated collagens (COL11A1, COL16A1, COL22A1, COL24A1, COL27A1, COL2A1, COL5A1, COL5A3, COL6A1, COL6A6, COL7A1, COL9A1) as these were present in multiple pathways such as the Collagen biosynthesis, Collagen degradation, Pulmonary Fibrosis Idiopathic Signaling Pathway, Wound Healing Signaling Pathway, GP6 Signaling Pathway, and Hepatic Fibrosis/ Hepatic Stellate Cell Activation pathways. This evidence concerns the gene COL16A1 and pulmonary fibrosis.