Conversely high SIRP-β2 expression on non M2-macrophages enhances phagocytosis of tumor cells [6], suggesting a potential SIRP-β2-SIRP-β2 interaction or an increased cytokine production by SIRP-β2 macrophages, that drives an ‘eat me’ signal in SIRP-β2high patients. Here, SIRPA is linked to neoplasm.