Its immunosuppressive mechanism specifically targets rapidly proliferating keratinocytes and attenuates the inflammatory cascade by diminishing pro-inflammatory cytokines, including TNF-α and IL-17, which are pivotal to the pathogenesis of psoriasis (Carrascosa et al. 2016; Rajitha et al. 2017; Friedman & Cronstein 2019; Elango et al. 2022). This evidence concerns the gene TNF and psoriasis.