The chemokines CCL2 and CCL5 well known attractants of CTLs as well as CXCL9 and CXCL10 powerful chemoattractant of activated CTLs were all highly induced by mIL12 mRNA treatment in both models and likely laid the ground for trafficking and retention of these effectors deep within the tumor cores. The gene discussed is CXCL9; the disease is neoplasm.