To test this, we assessed the expression of A1BG and DNA repair‐related proteins (PARP1, ATM, and p‐ATM) at various time points (0, 6, 12, and 24 h) following cisplatin treatment in osteosarcoma cells under A1BG‐depleted or recombinant A1BG‐supplemented conditions. This evidence concerns the gene PARP1 and osteosarcoma.