IDH1 and glioblastoma: When analyzing the cohort of 36 HGG individuals defined as having glioblastoma (GBM) according to WHO CNS5/2021, with IDH-wt per definition, the difference of max APTw, mean, and median APTw between MGMT methylated and non-methylated tumors was found to be non-significant (p = 0.078, 0.885; 0.601) (Tables S1 and S2).