NFKB1 and triple-negative breast carcinoma: In fact, it was shown that PsA-D attenuated NF-κB activation induced by lipopolysaccharide (LPS) and tumor necrosis factor-alpha (TNF-α) in both the human monocytic THP-1 cell line and the MDA-MB-231 triple-negative breast cancer (TNBC) cell line.