Neurofibromatosis type 1 (NF1) and Neurofibromatosis type 2 (NF2), tuberous sclerosis complex (TSC), von Hippel–Lindau disease (VHL), Sturge–Weber syndrome (SWS), and ataxia–telangiectasia (A-T) exemplify this group. Here, NF1 is linked to von Hippel-Lindau disease.