MMP2 and tuberculosis: Similarly, for discriminating both unconfirmed from unlikely TB cases, dual combinations like MMP1/MMP2 (AUC = 1, sensitivity = 100%, specificity = 100%), MMP1/MMP9 (AUC = 0.973, sensitivity = 94%, specificity = 90%), MMP2/MMP9 (AUC = 0.992, sensitivity = 97%, specificity = 100%), and triple combinations such as MMP1/MMP2/MMP9 (AUC = 1, sensitivity = 100%, specificity = 100%) were highly effective (Figure 5).