Receiver operating characteristic (ROC) analysis highlighted the robust discriminatory power of MMP-1 (AUC = 0.9581), MMP-2 (AUC = 1), and MMP-9 (AUC = 0.9940) in distinguishing confirmed TB from unlikely TB, with high area under the curve (AUC) values (Figure 4A). This evidence concerns the gene MMP1 and tuberculosis.