One of them is a selective JNK3 inhibitor called IQ-1S (sodium salt of 11H-indeno[1,2-b]quinoxalin-11-one oxime) [15], which, as shown in in silico and in vitro experiments, has strong affinity for JNK3, protects the brain after stroke in rats [16], and has anti-inflammatory properties [17]. The gene discussed is MAPK10; the disease is Stroke.