Several genes have been implicated in the pathogenesis of ALS, including superoxide dismutase 1 (SOD1), Fused in Sarcoma (FUS), chromosome 9 open reading frame 72 (C9orf72), and TAR DNA binding protein 43 (TDP-43) [120,121]. The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.