An autoimmune model of MS, experimental autoimmune encephalomyelitis (EAE), has also supported the autoimmune theory, where EAE can be induced by sensitization with CNS antigens, including myelin oligodendrocyte glycoprotein (MOG) and myelin proteolipid protein (PLP) [13,19,20]. The gene discussed is MOG; the disease is myeloid sarcoma.