TGFB1 and cancer: In cancer cells, STRAP has been found to be involved in several signal transduction pathways, including TGF-β, NOTCH, MEK/ERK, and Wnt/β-Catenin, that may contribute to signal transduction, transcriptional regulation, programmed cell death, EMT, invasion, RNA processing, chromatin assembly, cell cycle progression, and vesicular trafficking [5,7,8,15].