FASN and neoplasm: Previous studies have shown that downregulation of FASN can inhibit tumor growth.[37, 38] In bladder cancer, elevated expression of FASN has been associated with advanced tumor stage and poor overall survival.[39] In our analysis of TCGA data, FASN expression in bladder cancer was significantly higher than that in most other cancer types, suggesting that FASN may be an important driver in the development and progression of bladder cancer.