In colorectal tumors, P. distasonis has been shown to inhibit signaling via TLR4, MYD88, and Akt, and to promote apoptosis, exhibiting both anti‐inflammatory and anticancer effects.[29] However, the protective role of P. distasonis in bladder tumors has not yet been demonstrated. The gene discussed is TLR4; the disease is urinary bladder neoplasm.